King Willem-Alexander has appointed former LIFE Cooperative board members Ton Vries and Johannes Wolters as Officers of the Order of Orange-Nassau. The royal distinctions were festively presented by Mayor Roelien Kamminga of Groningen during the Life Science Conference of the LIFE Cooperative on Tuesday, September 23. The board and team of the cooperative are proud of this recognition, which honors the decades-long commitment and meaningful contributions of these leading figures in the Life Sciences, Health & MedTech sector in the Northern Netherlands—and far beyond.
Peter Ketelaar, Chair of the LIFE Cooperative Board: “We are incredibly proud of Johannes and Ton. Their dedication has truly shaped the Life Sciences, Health & MedTech sector, not only in the Northern Netherlands. Their commitment, expertise, and entrepreneurship have strengthened our cooperative and had a major societal and economic impact, both nationally and internationally!”
For most of his career, Johannes Wolters has been committed to advancing the Life Sciences, Health & MedTech sector in the Northern Netherlands, with a strong focus on societal and economic impact. From 2000 until his retirement earlier this year, he was the sole owner of Lode Holding—a more than 75-year-old company that flourished under his leadership. With subsidiaries Lode, ProCare, aXtion, Umaco, and Omnium, the group annually produces hundreds of medical devices and software solutions that contribute to health and rehabilitation worldwide. Almost every Olympic athlete improves their performance with equipment from Lode Holding.
Johannes initiated the Wenckebach project and other large-scale collaborative initiatives, invested millions in innovative medical ideas for diverse target groups, and helped establish numerous spin-offs. His work has directly supported thousands of patients every day. Until recently, he was active in regional initiatives such as SSIG (Sport Science & Innovation Groningen), the LIFE Cooperative (as co-founder), and the Campus Trail, while also mentoring young entrepreneurs and startups.
The next generation has since taken over the family business. Annelies Wolters, CEO of Lode Holding and daughter of Johannes: “My father has always dedicated himself to society and the well-being of others. Whether it’s medical innovation, supporting vulnerable groups, or inspiring young people in technology and science, his efforts have always been driven by responsibility, vision, and a deep sense of community.
For more than 35 years, Ton Vries has been a driving force in the Life Sciences & Health sector. From 2000 to 2020, he served as CEO of Syncom BV, which under his leadership grew into a successful spin-off of the University of Groningen. In 2017, he co-initiated the merger of Syncom and Mercachem, creating Symeres, a leading European contract research organization with over 600 employees worldwide.
Ton is the inventor of the Dutch Resolution, a method for efficiently separating chiral compounds. This breakthrough resulted in patents, publications, licensing agreements with DSM, and four PhD theses—solidifying the Netherlands’ international leadership in pharmaceutical crystallization technology and green chemistry.
He is also co-founder and CEO of BioBTX, a Groningen-based company with global impact that gives plastic waste a second life. Using its proprietary technology, residual waste streams are converted into valuable, circular building blocks for the chemical industry. The company is now preparing to build the world’s first circular aromatics plant in Delfzijl.
Ton co-founded the LIFE Cooperative, guided young entrepreneurs, and realized numerous groundbreaking projects. Personally, he is known for his no-nonsense attitude, boundless energy, and popularity among colleagues.
Robert Hof, former colleague at Symeres and LIFE Cooperative board member: “Ton is a true go-getter. When Syncom ran into trouble in 2008, he brought in new investors and rebuilt the company into the great success that Symeres is today. Ton is no-nonsense, not one for status or pretense. He doesn’t wear a suit—not even when Prime Minister Rutte or Queen Máxima visits. His company car? For years it was a 15-year-old Opel Astra, shared with the neighbor. With Ton, it’s always what you see is what you get. That directness and authenticity make him so beloved.”
"We are incredibly proud of Johannes and Ton. Their dedication has truly shaped the Life Sciences, Health & MedTech sector, not only in the Northern Netherlands. Their commitment, expertise, and entrepreneurship have strengthened our cooperative and had a major societal and economic impact, both nationally and internationally!"
Peter Ketelaar Chair of the board of the LIFE Cooperative
Roles & Organizations
1985: Joined Lode as Controller
1992: Conducted a management buyout with a partner from the then-American owners of Lode
2000: Became 100% owner and CEO of Lode; shortly after, founded additional companies and Lode Holding as the parent company. Between 2000–2025, led multiple acquisitions and participated in various ventures
2023: Next generation joins the company, solidifying Lode Holding as a family business
2025: Retired on May 1, passing leadership to daughter Annelies (CEO) and son Freek (CFO)
2014–2024: Co-founder & board member of LIFE Cooperative
Impact & Innovation
Produced over 1,000 medical devices, benefiting millions of patients worldwide
Projects spanning rehabilitation, sports, ADL equipment, prehabilitation & perioperative care
Co-initiated the Campus Trail running event with Campus Groningen (since 2017)
Sponsored scientific research and involved in initiatives such as Girls’ Day and student excursions
Societal Engagement
Mentored young entrepreneurs (>40 start-ups/year)
Volunteer at SSIG (Sport Science & Innovation Groningen), ~12 hours/week
Advisor and board member for RVO, Smitfonds, and juror in entrepreneurship competitions
Roles & Organizations
2000–2020: CEO of Syncom BV, growing the company from 30 to over 100 employees
2017: Merged Syncom and Mercachem to create Symeres, now with over 600 employees worldwide
Co-initiator of InnoLab Chemie, Cliq Swiss Tech, and BioBTX
2014–2024: Co-founder & Chair of LIFE Cooperative
2014–present: Board member of Campus Groningen
Current: Board member of PharmaNL
Innovation & Science
PhD in Organic Chemistry, 1996, University of Groningen under Professor Hans Wijnberg
Inventor of the Dutch Resolution method for separating chiral compounds
Patents, publications (e.g., Angewandte Chemie), DSM licensing, 4 PhDs supervised
Impact: more efficient and sustainable pharmaceutical production, strengthening Dutch expertise in pharmaceutical crystallization technology
Societal Engagement
Mentor and coach to young entrepreneurs and colleagues
Delivered notable projects within LIFE Cooperative
Personal reputation: no-nonsense, energetic, determined, highly respected by peers
Athletic: maintains daily long-distance running
Op zondag 31 mei 2026 staat Groningen in het teken van sport, doorzettingsvermogen en betrokkenheid. Tussen alle lopers is ook het herkenbare roze van Vrienden Beatrix Kinderziekenhuis zichtbaar.
The LIFE Cooperative, part of the Northern Netherlands life sciences ecosystem at Campus Groningen, is organizing the Dutch Medicines Winter Afternoon together with FIGON on Thursday, 26 February. This fully booked event brings together leading scientists and industry experts to explore the latest developments in innovative medicines and advanced drug delivery. Read the full article as published by the LIFE Cooperative.National Attention for Sold-Out Dutch Medicines Winter Afternoon: Innovative Medicines and Advanced Drug Delivery Take Center Stage in Groningen Innovation in medicines takes center stage on Thursday, 26 February during the Dutch Medicines Winter Afternoon, an inspiring event organized by FIGON (Federation for Innovative Drug Research Netherlands) in collaboration with the LIFE Cooperative. “We are extremely proud of the strong line-up at this event, bringing together leading experts from science and industry to explore the frontiers of drug development. The fact that registrations are already fully booked underlines the great importance of this event for the life sciences ecosystem, and in particular for the Northern Netherlands,” says Ronald Hesse, Director of the LIFE Cooperative. The Dutch Medicines Winter Afternoon brings together scientists, innovators, and professionals from across the Netherlands for an afternoon of insights, knowledge exchange, and networking opportunities. The speaker line-up features experts from both academia and industry. This event is already fully booked. Interested in joining the waiting list? Please email: amber@lifecooperative.nlConnecting force The afternoon will be opened by Prof. Klaas Poelstra of the University of Groningen (RUG), Chair of FIGON, who will outline the importance of innovative drug development in the Netherlands. This will be followed by an introduction by Robert Hof on behalf of the LIFE Cooperative, highlighting the cooperative’s role as a connecting force within the regional ecosystem. The first session block before the break focuses on innovation in drug delivery systems. Rob Steendam (CTO, InnoCore) will discuss the development of long-acting SynBiosys® microspheres for controlled and sustained drug release. Jaap Wieling (CEO, PureIMS) will present the potential of dry-powder inhalation via the Cyclops® technology for both pulmonary and systemic indications. From an academic perspective, Prof. Marleen Kamperman (University of Groningen) will explore the potential of polyelectrolyte coacervates as innovative drug delivery platforms.Deep dive After the break, the focus shifts to advanced nanomedicines and clinical development strategies. Dr. Flávia Sousa (RUG) will present her work on polymer-based nanomedicines for the delivery of biotherapeutics to the brain. Dr. Ad Roffel (ICON plc, Groningen) will address mass balance and absolute bioavailability studies with ¹⁴C-labeled drugs in humans, an essential component of clinical drug development. Prof. Erik Frijlink (RUG) will reflect on the value of innovation within both established and advanced drug delivery systems, placing technological progress in a broader pharmaceutical context. Finally, Prof. Helder Santos (RUG) will demonstrate how nanomedicines are being used for RNA delivery in myocardial infarction repair, a promising development in cardiovascular therapy. “We are extremely proud of the strong line-up at this event, bringing together leading experts from science and industry to explore the frontiers of drug development. The fact that registrations are already fully booked underlines the great importance of this event for the life sciences ecosystem, and in particular for the Northern Netherlands." - Ronald Hesse, director LIFE CooperativeClosing and networking The afternoon will conclude with a contribution by Peter Ketelaar (LIFE Cooperative), followed by closing remarks from Prof. Klaas Poelstra. Participants will then have the opportunity to connect and continue discussions during the networking reception. Hesse looks forward to the event: “With this event, FIGON and the LIFE Cooperative underline the strength of collaboration between academia, industry, and clinical practice. The Dutch Medicines Winter Afternoon promises not only to be an inspiring afternoon, but also to provide momentum for further innovation and collaboration within the Northern Netherlands life sciences ecosystem.” Text: lifecooperative.nlPhotographer: Casper Maas
The master plan for the Healthy Ageing Campus has officially been approved! This marks an important step in developing the campus as a hub for knowledge, innovation, and collaboration. With a focus on greenery, health, and connection to the city, the campus will become a vibrant environment where research, education, healthcare, and business come together. The vision provides space for new laboratories, building renovations, meeting places, and closer collaboration between UMCG, RUG, and the business community. Read the whole article by the UMCG below.Green light for the Healthy Ageing Campus Master Plan On Wednesday, 18 February 2026, the Groningen City Council formally approved the master plan for the Healthy Ageing Campus. This is a major milestone, as the plan provides the framework for the campus’s further development and its integration with the surrounding area. At the end of last year, the University of Groningen (RUG), the University Medical Center Groningen (UMCG), and the City of Groningen presented an ambitious, future-proof plan for the campus. Shared ambitions have been translated into coherent spatial and programmatic guidelines for current and future developments. In other words: how much space is available for which functions on the campus, and where is the most suitable location for them? The renewed campus will: Provide space for knowledge, innovation, and collaboration, encouraging interaction between disciplines and people; Connect with the city, making the campus a natural part of Groningen life; Be a healthy and sustainable environment, with attention to greenery, physical activity, wellbeing, and a living environment that supports health; Be lively and accessible, bringing together living, working, research, studying, and healthcare.Next steps The master plan is not only a blueprint for the future, but also a concrete step toward further developing the current campus. Construction and renovation on the UMCG and RUG grounds are ongoing, and each project must now be assessed to determine what is possible. With the approval of this master plan, the way is cleared for follow-up decisions, including applying for demolition and building permits and further project development within the area. Upcoming projects include: The construction of the Central Laboratory for Diagnostics and Research (CLDR): a new laboratory building on the site of the former UCP building. This building will bring together various laboratories in one location to improve collaboration. Relocating laboratories from the Central Medical Complex is also necessary for the renovation and expansion of several hospital departments; Renovation and future-proofing of existing UMCG and RUG buildings, with attention to sustainability, flexibility, and integration with the heating/cooling system; Making the campus greener and more accessible, creating new meeting places and better connections to surrounding public spaces; Creating space for campus-related business activities, strengthening collaboration between UMCG, RUG, and the private sector.Municipality explores the future of DOT Initially, the master plan covered the area between Petrus Campersingel and Oostersingel, from Hanzeplein to the Oosterhamrikkanaal. In the newly approved plan, the Bodenterrein site has been separated, as the municipality is investigating the costs of possibly preserving DOT. More information on this will be available later this year. Read more about the Master Plan.Source text and pictures: umcg.nl